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PCR-based differentiation of Fasciola species (Trematoda: Fasciolidae), using primers based on RAPD-derived sequences.
(Elsevier Ltd., 2007)
The zoonotic liver flukes Fasciola hepatica and F. gigantica co-exist in parts of Africa and Asia. The two species have similar life-cycles but different transmission characteristics. Although the identification of adult ...
The egg hatch test: A useful tool for albendazole resistance diagnosis in Fasciola hepatica.
(Elsevier B.V., 2019)
In the current study, the egg hatch test (EHT) has been evaluated as an in vitro technique to detect albendazole (ABZ) resistance in Fasciola hepatica. The intra- and inter-assay variations of the EHT were measured by means ...
Mitochondrial genome analysis supports zoonotic transmission of triclabendazole-resistant human fascioliasis in Peru.
(Elsevier B.V., 2025)
Fascioliasis is a parasitic infection caused by Fasciola spp., primarily affecting ruminant animals. These digenean flatworms cause severe liver damage in their hosts, resulting in substantial economic losses within the ...
A single amino acid substitution in isozyme GST mu in Triclabendazole resistant Fasciola hepatica (Sligo strain) can substantially influence the manifestation of anthelmintic resistance.
(Academic Press Inc., 2015)
The helminth parasite Fasciola hepatica causes fascioliasis in human and domestic ruminants. Economic losses due to this infection are estimated in U$S 2000-3000 million yearly. The most common method of control is the use ...
Molecular characterization and phylogenetic analysis of Fasciola hepatica from Peru.
(Elsevier Ireland Ltd., 2016)
The causative agent of fasciolosis in South America is thought to be Fasciola hepatica. In this study, Fasciola flukes from Peru were analyzed to investigate their genetic structure and phylogenetic relationships with those ...
Independent origins and non-parallel selection signatures of triclabendazole resistance in Fasciola hepatica.
(Nature Research., 2025)
Triclabendazole (TCBZ) is the primary treatment for fascioliasis, a global foodborne zoonosis caused by Fasciola hepatica. Widespread resistance to TCBZ (TCBZ-R) in livestock and a rapid rise in resistant human infections ...
Oxfendazole flukicidal activity in pigs
(Elsevier, 2014-03-28)
Although oxfendazole (OFZ) is a well know broad-spectrum benzimidazole anthelmintic, the assessment
of its potential trematodicidal activity remains unexplored. OFZ administration at single high doses has
been recommended ...
Western blot technique standardization of the diagnosis of human fasciolosis using Fasciola hepatica excreted-secreted antigens.
(Instituto Nacional de Salud., 2011)
Objectives: To evaluate the performance of the enzyme-linked immunoelectrotransfer blot assay (EITB, Western blot) using excretory/secretory antigens from adult forms of Fasciola hepatica (Fh E/S Ag) for the diagnosis of ...
Distinct gut microbiome features characterize Fasciola hepatica infection and predict triclabendazole treatment outcomes in Peruvian patients.
(Frontiers Media SA., 2025)
Background Fasciola hepatica, a globally distributed helminth, causes fasciolosis, a disease with significant health and economic impacts. Variability in triclabendazole (TCBZ) efficacy and emerging resistance are remaining ...
Fasciola hepatica phenotypic characterization in Andean human endemic areas: Valley versus altiplanic patterns analysed in liver flukes from sheep from Cajamarca and Mantaro, Peru.
(Elsevier Ltd, 2012)
Fascioliasis is a zoonotic parasitic disease caused by Fasciola hepatica and Fasciola gigantica. Of both species, F. hepatica is the only one described in the Americas, mainly transmitted by lymnaeid snail vectors of the ...
