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A single amino acid substitution in isozyme GST mu in Triclabendazole resistant Fasciola hepatica (Sligo strain) can substantially influence the manifestation of anthelmintic resistance.

Fernández, V.; Estein, S.; Ortiz-Oblitas, P.; Luchessi, P.; Solana, V.; Solana, H. (Academic Press Inc., 2015)

The helminth parasite Fasciola hepatica causes fascioliasis in human and domestic ruminants. Economic losses due to this infection are estimated in U$S 2000-3000 million yearly. The most common method of control is the use ...

Resistance of Fasciola hepatica against Triclabendazole in cattle in Cajamarca (Peru): A clinical trial and an in vivo efficacy test in sheep

Ortiz-Oblitas, P.; Scarcella, S.; Cerna, C.C.; Rosales Loredo, C.; Cabrera, M.; Guzmán, M.; Lamenza, P.; Solana, H. (Elsevier., 2013-07-01)

Fasciolosis caused by Fasciola hepatica, is the most prevalent parasitic disease in dairy cattle from the northern region of Cajamarca, Peru. The control of this parasite is based on the use of Triclabendazole (TCBZ), a ...