Listar por autor "Fernandez-Baca, M.V."
Mostrando ítems 1-5 de 5
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A PCR Test Using the Mini-PCR Platform and Simplified Product Detection Methods Is Highly Sensitive and Specific to Detect Fasciola hepatica DNA Mixed in Human Stool, Snail Tissue, and Water DNA Specimens.
Fernandez-Baca, M.V.; Castellanos-González, A.; Ore, R.A.; Alccacontor-Munoz, J.L.; Hobán-Vergara, C.; Castro, C.A.; Tanabe, M.B.; Morales, M.L.; Ortiz-Oblitas, P.; White, A.C.; Cabada, M.M. (Multidisciplinary Digital Publishing Institute (MDPI)., 2024)Fasciola hepatica has a complex lifecycle with multiple intermediate and definitive hosts and influenced by environmental factors. The disease causes significant morbidity in children and its prevalent worldwide. There is ... -
Distinct gut microbiome features characterize Fasciola hepatica infection and predict triclabendazole treatment outcomes in Peruvian patients.
Lee, G.; Rosa, B.A.; Fernandez-Baca, M.V.; Martin, J.; Ore, R.A.; Ortiz-Oblitas, P.; Cabada, M.M.; Mitreva, M. (Frontiers Media SA., 2025)Background Fasciola hepatica, a globally distributed helminth, causes fasciolosis, a disease with significant health and economic impacts. Variability in triclabendazole (TCBZ) efficacy and emerging resistance are remaining ... -
Independent origins and non-parallel selection signatures of triclabendazole resistance in Fasciola hepatica.
Choi, Y.-J.; Rosa, B.A.; Fernandez-Baca, M.V.; Ore, R.A.; Martin, J.; Ortiz-Oblitas, P.; Hobán-Vergara, C.; Cabada, M.M.; Mitreva, M. (Nature Research., 2025)Triclabendazole (TCBZ) is the primary treatment for fascioliasis, a global foodborne zoonosis caused by Fasciola hepatica. Widespread resistance to TCBZ (TCBZ-R) in livestock and a rapid rise in resistant human infections ... -
Mitochondrial genome analysis supports zoonotic transmission of triclabendazole-resistant human fascioliasis in Peru.
Kumar, P.; Choi, Y.-J.; Fernandez-Baca, M.V.; Ore, R.A.; Morales, M.L.; Ortiz-Oblitas, P.; Hobán-Vergara, C.; Cabada, M.M.; Mitreva, M. (Elsevier B.V., 2025)Fascioliasis is a parasitic infection caused by Fasciola spp., primarily affecting ruminant animals. These digenean flatworms cause severe liver damage in their hosts, resulting in substantial economic losses within the ... -
The Differences in the Susceptibility Patterns to Triclabendazole Sulfoxide in Field Isolates of Fasciola hepatica Are Associated with Geographic, Seasonal, and Morphometric Variations.
Fernandez-Baca, M.V.; Hobán-Vergara, C.; Ore, R.A.; Ortiz-Oblitas, P.; Choi, Y.-J.; Murga-Moreno, C.A.; Mitreva, M.; Cabada, M.M. (MDPI., 2022)Triclabendazole (TCBZ) resistance is an emerging problem in fascioliasis that is not well understood. Studies including small numbers of parasites fail to capture the complexity of susceptibility variations between and ...






