• Oxfendazole flukicidal activity in pigs 

      Ortiz-Oblitas, P.; Terrones, S.; Cabrera, M.; Hobán-Vergara, C.; Ceballos, L.; Moreno, L.; Canton, C.; Donadeu, M.; Lanusse, C.; Álvarez, L. (ElsevierPE, 2014-03-28)
      Although oxfendazole (OFZ) is a well know broad-spectrum benzimidazole anthelmintic, the assessment of its potential trematodicidal activity remains unexplored. OFZ administration at single high doses has been recommended ...
    • Pharmacokinetic evaluation of different generic triclabendazole formulations in heifers. 

      Ortiz-Oblitas, P.; Castope, N.; Cabrera, M.; Farías, C.; Suárez, G.; Lanusse, C.; Álvarez, L. (Taylor and Francis Ltd., 2014)
      AIMS: To assess the comparative drug systemic exposure of a reference (RF) and four test (Test I, Test II, Test III and Test IV) formulations of triclabendazole (TCBZ) in heifers. METHODS: Thirty Holstein heifers were ...
    • Residual concentrations of the flukicidal compound triclabendazole in dairy cows' milk and cheese. 

      Imperiale, F.; Ortiz-Oblitas, P.; Cabrera, M.; Farías, C.; Sallovitz, J.M.; Iezzi, S.; Pérez-Arévalo, J.; Álvarez, L.; Lanusse, C. (Taylor and Francis Ltd., 2011)
      Triclabendazole (TCBZ) is a flukicidal halogenated benzimidazole compound extensively used in veterinary medicine. Liver fluke control in lactating dairy cattle is difficult because treatment should be implemented only ...
    • Testing albendazole resistance in Fasciola hepatica: Validation of an egg hatch test with isolates from South America and the United Kingdom. 

      Canevari, J.; Ceballos, L.; Sanabria, R.; Romero, J.; Olaechea, F.; Ortiz-Oblitas, P.; Cabrera, M.; Gayo, V.; Fairweather, I.; Lanusse, C.; Álvarez, L. (Cambridge University Press., 2014)
      The main goal of the current work was to develop and validate an in vitro fluke egg hatch test, as a method for the detection of albendazole (ABZ) resistance in the liver fluke, Fasciola hepatica. Fluke eggs (200/ml, n= ...
    • The egg hatch test: A useful tool for albendazole resistance diagnosis in Fasciola hepatica. 

      Ceballos, L.; Canton, C.; Pruzzo, C.; Sanabria, R.; Moreno, L.; Sanchís, J.; Suárez, G.; Ortiz-Oblitas, P.; Fairweather, I.; Lanusse, C.; Álvarez, L.; Martínez-Valladares, M.M. (Elsevier B.V., 2019)
      In the current study, the egg hatch test (EHT) has been evaluated as an in vitro technique to detect albendazole (ABZ) resistance in Fasciola hepatica. The intra- and inter-assay variations of the EHT were measured by means ...
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